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AB5230-200UL Anti-Calcium Channel Antibody, Voltage Gated β3

This Anti-Calcium Channel Antibody, Voltage Gated β3 is validated for use in WB for the detection of Calcium Channel.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Ion Channels & Transporters, Signaling Neuroscience Gene Symbol: CACNB3, CACNLB3, CAB3 UniProt Number: P54284
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AB5230-200UL
200 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB5230-200UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Calcium Channel Antibody, Voltage Gated β3
      Alternate Names
      • CAB3
      • Dihydropyridine-sensitive L-type
      • Calcium Channel beta-3 Subunit
      • Voltage-dependent Calcium Channel beta-3 Subunit
      References
      Product Information
      FormatPurified
      Control
      • CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
      PresentationPurified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Calcium Channel Antibody, Voltage Gated β3 is validated for use in WB for the detection of Calcium Channel.
      Key Applications
      • Western Blotting
      Application NotesWestern blot: 1:200-1:300 using ECL on rat brain membranes.

      Dilutions should be made using a carrier protein such as BSA (1-3%)

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenA purified peptide corresponding to amino acid residues 463-477 of rabbit Ca beta3 (Accession number P54286).
      EpitopeVoltage Gated beta3
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes the full length Ca beta3 protein, not with other known proteins tested so far.
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CACNB3
      • CACNLB3
      • CAB3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P54284 # The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
      SIZE: 484 amino acids; 54532 Da
      SUBUNIT: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with CACNA2D4.
      TISSUE SPECIFICITY: Expressed mostly in brain, smooth muscle and ovary.
      SIMILARITY: SwissProt: P54284 ## Belongs to the calcium channel beta subunit family. & Contains 1 SH3 domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB5230-200UL 04053252402265

      Documentation

      Anti-Calcium Channel Antibody, Voltage Gated β3 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Calcium Channel Antibody, Voltage Gated β3 Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3766680
      RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2193329 2193329
      RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2318797 2318797

      Data Sheet

      Title
      RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY