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AB9285 Anti-Somatostatin Receptor Type 3 Antibody

This Anti-Somatostatin Receptor Type 3 Antibody is validated for use in IH(P) for the detection of Somatostatin Receptor Type 3.

Anti-Somatostatin Receptor Type 3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: CNS Control of Metabolism, Hormones & Receptors Gene Symbol: SSTR3, SS3R, OTTHUMP00000028737, SSR-28 UniProt Number: P32745
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AB9285
50 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9285
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Somatostatin Receptor Type 3 Antibody
      Alternate Names
      • SSTR3
      References
      Product Information
      FormatAffinity Purified
      HS Code3002 15 90
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Somatostatin Receptor Type 3 Antibody is validated for use in IH(P) for the detection of Somatostatin Receptor Type 3.
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on paraffin embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the C-terminal domain of human Somatostatin Receptor Type 3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Somatostatin Receptor Type 3 [SSTR3].
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummarySomatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.
      Gene Symbol
      • SSTR3
      • SS3R
      • OTTHUMP00000028737
      • SSR-28
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P32745 # Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
      SIZE: 418 amino acids; 45847 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity).
      TISSUE SPECIFICITY: Brain, pituitary and pancreas.
      PTM: Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).
      SIMILARITY: SwissProt: P32745 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9285 04053252407857

      Documentation

      Anti-Somatostatin Receptor Type 3 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Somatostatin Receptor Type 3 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2453318 2453318
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 3 - 3946900 3946900
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2227159 2227159

      References

      Reference overviewPub Med ID
      Immunohistochemical expression and localization of somatostatin receptor subtypes in androgen ablated prostate cancer
      Mazzucchelli R, Morichetti D, Santinelli A, Scarpelli M, Bono AV, Lopez-Beltran A, Cheng L, Montironi R. Source Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
      Analytical Cellular Pathology / Cellular Oncology  33  27–36  2010

      Show Abstract       		20966542 20966542