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ABC827 Anti-IFITM1 Antibody

This Anti-IFITM1 Antibody is validated for use in western blotting, ICC & immunofluorescence for the detection of IFITM1.

Anti-IFITM1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: IFITM1, CD225, IFI17 UniProt Number: P13164
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ABC827
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC827
      DescriptionAnti-IFITM1 Antibody
      Alternate Names
      • Interferon-induced transmembrane protein 1
      • Dispanin subfamily A member 2a
      • DSPA2a
      • Interferon-induced protein 17
      • Interferon-inducible protein 9-27
      • Leu-13 antigen
      • CD225
      Background InformationInterferon-induced transmembrane protein 1, also known as Dispanin subfamily A member 2a (DSPA2a) or Interferon-induced protein 17 or Interferon-inducible protein 9-27 or Leu-13 antigen or CD225, and encoded by the gene name IFITM1 or CD225 is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-γ-induced antiproliferation and plays a role in the control of cell growth and migration. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-IFITM1 Antibody is validated for use in western blotting, ICC & immunofluorescence for the detection of IFITM1.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunofluorescence
      Application NotesImmunocytochemistry Analysis: 20 μg/mL from a representative lot detected IFITM1 in Jurkat cells.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected IFITM1 in Jurkat cells.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the center region of human IFITM1.
      Epitopecenter region
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody will cross-react with IFITM2 and IFITM3.
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • IFITM1
      • CD225
      • IFI17
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~14 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in NIH/3T3 cell lysate.

      Western Blotting Analysis: 2 μg/mL of this antibody detected IFITM1 in NIH/3T3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC827 04053252943867