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ABS224 Anti-YVH1 Antibody

Anti-YVH1 Antibody is an antibody against YVH1 for use in Western Blotting.

Anti-YVH1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Kinases & Phosphatases Gene Symbol: DUSP12 UniProt Number: Q9UNI6
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ABS224
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS224
      DescriptionAnti-YVH1 Antibody
      Alternate Names
      • Dual specificity protein phosphatase 12
      • Dual specificity tyrosine phosphatase YVH1
      Background InformationYeast VH1-related phosphatase (YVH1), also known as “dual specificity protein phosphatase 12” (DUSP12) is a ubiquitous phosphatase, with relatively high levels of expression in the ovary, testis, spleen, and peripheral blood leukocytes. YVH1 primarily removes phosphate groups from phosphorylated serine, threonine, and tyrosine residues in its target substrates. However, YVH1 also contains a zinc-binding domain which may enable it to interact with other proteins involved in cell growth, cell survival, and cell cycle progression. YVH1 may also be involved in the assembly of ribosomes, and in the biogenesis of the 60S ribosomal subunit. It can be targeted to different subcellular locations by phosphorylation of its Ser335 residue located in the zinc-binding domain.
      References
      Product Information
      FormatAffinity Purified
      Control
      • HeLa cells
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-YVH1 Antibody is an antibody against YVH1 for use in Western Blotting.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot Analysis: A representative lot detected YVH1 in 10 µg of Jurkat cell lysate.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human YVH1.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DUSP12
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~38 kDa observed. An uncharacterized band at ~36 kDa may be observed in some cell lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa cells.

      Western Blot Analysis: A 1:500 dilution of this antibody detected YVH1 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS224 04053252522758

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies