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AG243 Midkine, recombinant human

Midkine, recombinant human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Positive Control UniProt Number: P21741 Entrez Gene Number: NM_001012333.1, NM_001012334.1, NM_002391.3
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AG243
20 µg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberAG243
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionMidkine, recombinant human
      OverviewHuman Midkine (MK) is a new member of the heparin-binding neurotrophic factor family. MK and PTN (Pleiotrophin) are structural homologs, and are highly conserved among species. MK plays important roles in development and carcinogensis and has several important biological effects, including promotion of neurite extension and neuronal survival. Recombinant Midkine is a 13.4 kDa protein, comprising of 123 amino acid residues.
      References
      Product Information
      PresentationLyophilized from 0.4x PBS, pH 7.4.
      Quality LevelMQ100
      Applications
      Key Applications
      • Positive Control
      Biological Information
      PurityGreater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per mg of MK.
      SourceE.coli
      Entrez Gene Number
      Gene Symbol
      • MDK
      • ARAP
      • FLJ27379
      • MK1
      • NEGF2
      • MK
      • midkine
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P21741 # Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).
      SIZE: 143 amino acids; 15585 Da
      SUBUNIT: Homodimer.
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P21741 ## Belongs to the pleiotrophin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into water or other buffered solutions. Reconstitute MK should be stored in undiluted aliquots at -20°C for up to 6 months.
      Packaging Information
      Material Size20 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AG243 04053252580970