07-623 | Anti-Clara Cell Secretory Protein Antibody

07-623
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RIHC, WBRbSerumPolyclonal Antibody
      Description
      Catalogue Number07-623
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Clara Cell Secretory Protein Antibody
      References
      Product Information
      FormatSerum
      Control
      • Lung tissue
      PresentationRabbit antiserum containing 0.05% sodium azide and 30% glycerol.
      Applications
      ApplicationDetect Clara Cell Secretory Protein using this Anti-Clara Cell Secretory Protein Antibody validated for use in IH & WB.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Biological Information
      ImmunogenA synthetic peptide corresponding to amino acids 45-68 of mouse CCSP coupled to KLH
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Clara Cell Secretory Protein.
      IsotypeIgG
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SCGB1A1
      • UP1
      • uteroglobin
      • CC10
      • CC16
      • CCPBP
      • UGB
      • CCSP
      Purification MethodUnpurified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P11684 # Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
      SIZE: 91 amino acids; 9994 Da
      SUBUNIT: Homodimer; antiparallel disulfide-linked.
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).
      SIMILARITY: SwissProt: P11684 ## Belongs to the secretoglobin family.
      Molecular Weight10 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot in mouse lung nuclear extracts
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Clara Cell Secretory Protein (rabbit antiserum) - 2458932 2458932
      Anti-Clara Cell Secretory Protein (rabbit antiserum) 2930534
      Anti-Clara Cell Secretory Protein (rabbit antiserum) 2982296
      Anti-Clara Cell Secretory Protein (rabbit antiserum) - 2031433 2031433
      Anti-Clara Cell Secretory Protein (rabbit antiserum) - 2203124 2203124
      Anti-Clara Cell Secretory Protein (rabbit antiserum) - 2280810 2280810
      Anti-Clara Cell Secretory Protein (rabbit antiserum) - 2326267 2326267
      Anti-Clara Cell Secretory Protein (rabbit antiserum) -2508786 2508786
      Anti-Clara Cell Secretory Protein - 0610042769 0610042769
      Anti-Clara Cell Secretory Protein - 2064522 2064522

      References

      Reference overviewApplicationSpeciesPub Med ID
      Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene.
      Wang, Y; Xu, Z; Mao, JH; Hung, MS; Hsieh, D; Au, A; Jablons, DM; You, L
      Thoracic cancer  6  480-7  2015

      Show Abstract
      26273405 26273405
      Alveolar progenitor and stem cells in lung development, renewal and cancer.
      Desai, TJ; Brownfield, DG; Krasnow, MA
      Nature  507  190-4  2014

      Show Abstract
      Immunohistochemistry24499815 24499815
      In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.
      Maddalo, D; Manchado, E; Concepcion, CP; Bonetti, C; Vidigal, JA; Han, YC; Ogrodowski, P; Crippa, A; Rekhtman, N; de Stanchina, E; Lowe, SW; Ventura, A
      Nature  516  423-7  2014

      Show Abstract
      25337876 25337876
      Rapid modelling of cooperating genetic events in cancer through somatic genome editing.
      Sánchez-Rivera, FJ; Papagiannakopoulos, T; Romero, R; Tammela, T; Bauer, MR; Bhutkar, A; Joshi, NS; Subbaraj, L; Bronson, RT; Xue, W; Jacks, T
      Nature  516  428-31  2014

      Show Abstract
      25337879 25337879
      Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement.
      Tanaka, Y; Shigemura, N; Kawamura, T; Noda, K; Isse, K; Stolz, DB; Billiar, TR; Toyoda, Y; Bermudez, CA; Lyons-Weiler, J; Nakao, A
      Biochemical and biophysical research communications  425  873-9  2012

      Show Abstract
      22902635 22902635
      Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset.
      Xu, YD; Cui, JM; Wang, Y; Yin, LM; Gao, CK; Liu, XY; Wei, Y; Liu, YY; Jiang, YL; Shan, CX; Yang, YQ
      Evidence-based complementary and alternative medicine : eCAM  2012  850512  2012

      Show Abstract
      Western Blotting23304218 23304218
      Local fetal lung renin-angiotensin system as a target to treat congenital diaphragmatic hernia.
      Nogueira-Silva, C; Carvalho-Dias, E; Piairo, P; Nunes, S; Baptista, MJ; Moura, RS; Correia-Pinto, J
      Molecular medicine (Cambridge, Mass.)  18  231-43  2012

      Show Abstract
      ImmunohistochemistryRat22113494 22113494
      Loss of Rab27 function results in abnormal lung epithelium structure in mice.
      Bolasco, G; Tracey-White, DC; Tolmachova, T; Thorley, AJ; Tetley, TD; Seabra, MC; Hume, AN
      American journal of physiology. Cell physiology  300  C466-76  2011

      Show Abstract Full Text Article
      21160031 21160031
      Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells.
      De Paepe, ME; Mao, Q; Ghanta, S; Hovanesian, V; Padbury, JF
      The American journal of pathology  178  1329-39  2011

      Show Abstract
      21356383 21356383
      Lung tissue regeneration after induced injury in Runx3 KO mice.
      Jong-Min Lee,Hyuk-Jae Kwon,Suk-Chul Bae,Han-Sung Jung
      Cell and tissue research  341  2010

      Show Abstract
      20623301 20623301