06-709 | Anti-Gq/11α Antibody, CT

06-709
50 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MIP, WBRbPurifiedPolyclonal Antibody
      Description
      Catalogue Number06-709
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Gq/11α Antibody, CT
      References
      Product Information
      FormatPurified
      PresentationPBS, pH 7.4
      Applications
      ApplicationThis Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      Immunogenpeptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α
      HostRabbit
      SpecificityGqα and G11α
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GNA11
      • GA11
      • GNA-11
      Purification MethodProtein A chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P29992 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.
      SIZE: 359 amino acids; 42123 Da
      SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
      SIMILARITY: SwissProt: P29992 ## Belongs to the G-alpha family. G(q) subfamily.
      Molecular Weight42kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on rat brain microsomal preparation
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Gq/11#945;, CT (rabbit polyclonal IgG) - 2091717 2091717
      Anti-Gq/11#945;, CT (rabbit polyclonal IgG) - 2122433 2122433
      Anti-Gq/11#945;, CT - DAM1810812 DAM1810812
      Anti-Gq/11#945;, CT - JBC1860891 JBC1860891
      Anti-Gq/11a, CT (rabbit polyclonal IgG) 2952616
      Anti-Gq/11a, CT (rabbit polyclonal IgG) 2893304
      Anti-Gq/11a, CT (rabbit polyclonal IgG) - 2148235 2148235
      Anti-Gq/11a, CT (rabbit polyclonal IgG) - NG1901828 NG1901828
      Anti-Gq/11a, CT (rabbit polyclonal IgG) - NG1926403 NG1926403
      Anti-Gq/11a, CT - 1969691 1969691

      References

      Reference overviewPub Med ID
      Down-regulation of G-protein-mediated Ca2+ sensitization in smooth muscle.
      Gong, M C, et al.
      Mol. Biol. Cell, 8: 279-86 (1997)  1997

      Show Abstract
      9190207 9190207
      4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
      Blanc, E M, et al.
      J. Neurochem., 69: 570-80 (1997)  1997

      Show Abstract
      9231714 9231714
      Association of the G protein alpha(q)/alpha11-subunit with cytoskeleton in adrenal glomerulosa cells: role in receptor-effector coupling.
      Côté, M, et al.
      Endocrinology, 138: 3299-307 (1997)  1997

      Show Abstract
      9231781 9231781
      Specific coupling of a cation-sensing receptor to G protein alpha-subunits in MDCK cells.
      Arthur, J M, et al.
      Am. J. Physiol., 273: F129-35 (1997)  1997

      9249600 9249600
      Involvement of G alpha q/11 in the contractile signal transduction pathway of muscarinic M3 receptors in caecal smooth muscle.
      Cuq, P, et al.
      Eur. J. Pharmacol., 315: 213-9 (1996)  1996

      Show Abstract
      8960886 8960886
      G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.
      Kühn, B, et al.
      Mol. Endocrinol., 10: 1697-707 (1996)  1996

      Show Abstract
      8961278 8961278
      Characterization and use of crude alpha-subunit preparations for quantitative immunoblotting of G proteins.
      Gettys, T W, et al.
      Anal. Biochem., 220: 82-91 (1994)  1994

      Show Abstract
      7978261 7978261

      Data Sheet

      Title
      Anti-Gq/11α, CT