04-901 | Anti-NR2A Antibody, clone A12W, rabbit monoclonal

04-901
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RWBRbCulture SupernatantMonoclonal Antibody
      Description
      Catalogue Number04-901
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-NR2A Antibody, clone A12W, rabbit monoclonal
      References
      Product Information
      FormatCulture Supernatant
      PresentationCultured supernantant in 0.05% sodium azide
      Applications
      ApplicationAnti-NR2A Antibody, clone A12W is an antibody against NR2A for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      Immunogen6His-tagged fusion protein corresponding to amino acids 1265-1464 of mouse NMDA receptor 2A (NR2A)
      CloneA12W
      HostRabbit
      SpecificityNR2A
      IsotypeIgG
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GRIN2A
      • hNR2A
      • Glutamate
      • NMDAR2A
      • NR2A
      UniProt Number
      Molecular WeightMr 170kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on rat brain microsomal preparations (Catalog#12-144)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-NR2A, clone A12W - 2388921 2388921
      Anti-NR2A, clone A12W - NG1811032 NG1811032
      Anti-NR2A, clone A12W - 2161180 2161180
      Anti-NR2A, clone A12W - DAM1502747 DAM1502747
      Anti-NR2A, clone A12W - JH1784805 JH1784805
      Anti-NR2A, clone A12W - NG1845569 NG1845569
      Anti-NR2A, clone A12W - NG1859584 NG1859584
      Anti-NR2A, clone A12W - NG1927062 NG1927062
      Anti-NR2A, clone A12W -2517864 2517864
      Anti-NR2A, clone A12W -2578573 2578573

      References

      Reference overviewApplicationPub Med ID
      Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.
      Murata, Y; Constantine-Paton, M
      The Journal of neuroscience : the official journal of the Society for Neuroscience  33  5040-52  2013

      Show Abstract
      Western Blotting23486974 23486974
      Gestational methylazoxymethanol exposure leads to NMDAR dysfunction in hippocampus during early development and lasting deficits in learning.
      Snyder, MA; Adelman, AE; Gao, WJ
      Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology  38  328-40  2013

      Show Abstract
      Western Blotting22968815 22968815
      α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors adopt different subunit arrangements.
      Balasuriya, D; Goetze, TA; Barrera, NP; Stewart, AP; Suzuki, Y; Edwardson, JM
      The Journal of biological chemistry  288  21987-98  2013

      Show Abstract
      23760273 23760273
      Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging.
      Suzuki, Y; Goetze, TA; Stroebel, D; Balasuriya, D; Yoshimura, SH; Henderson, RM; Paoletti, P; Takeyasu, K; Edwardson, JM
      The Journal of biological chemistry  288  778-84  2013

      Show Abstract
      Western Blotting23223336 23223336
      Genetic deletion of NR3A accelerates glutamatergic synapse maturation.
      Henson, MA; Larsen, RS; Lawson, SN; Pérez-Otaño, I; Nakanishi, N; Lipton, SA; Philpot, BD
      PloS one  7  e42327  2012

      Show Abstract
      Western Blotting22870318 22870318
      Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
      Kiraly, DD; Lemtiri-Chlieh, F; Levine, ES; Mains, RE; Eipper, BA
      The Journal of neuroscience : the official journal of the Society for Neuroscience  31  12554-65  2011

      Show Abstract
      21880917 21880917

      Brochure

      Title
      Pathways and Biomarkers of Glutamatergic Synapse Flyer

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies