07-531 | Anti-PIR121-1/Sra-1 Antibody

200 µg  
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      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MIP, WBRbPurifiedPolyclonal Antibody
      Catalogue Number07-531
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-PIR121-1/Sra-1 Antibody
      Alternate Names
      • Cytoplasmic FMR1-interacting protein 1
      • Specifically Rac1-associated protein 1
      • Sra-1
      • p140sra-1
      Product Information
      ApplicationAnti-PIR121-1/Sra-1 Antibody is an antibody against PIR121-1/Sra-1 for use in IP & WB.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated, synthetic peptide corresponding to amino acids 872-886 (SQEFQRDKQPNAQPQ-C) of human PIR121-1/Sra-1, with a C-terminal cysteine added for conjugation purposes.
      SpecificityPIR121-1/Sra-1 (aka CYFIP1)
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CYFIP1
      • KIAA0068
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular WeightMr~130kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on RIPA homogenates from rat brain
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditionsstable 2 years at -20°C from date of shipment
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-PIR121-1/Sra-1 (rabbit polyclonal IgG) 2953776
      Anti-PIR121-1/Sra-1 (rabbit polyclonal IgG) 2902702
      Anti-PIR121-1/Sra-1 (rabbit polyclonal IgG) 2986156
      Anti-PIR121-1/Sra-1 (rabbit polyclonal IgG) -2474977 2474977
      Anti-PIR121-1/Sra-1 - 26713 26713
      Anti-PIR121-1/Sra-1 -2639573 2639573
      Anti-PIR121-1/Sra-1 -2659671 2659671
      Anti-PIR121-1/Sra-1 -2676596 2676596
      Anti-PIR121-1/Sra-1 -2703674 2703674
      Anti-PIR121-1/Sra-1 -2785817 2785817


      Reference overviewApplicationPub Med ID
      BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.
      Genheden, M; Kenney, JW; Johnston, HE; Manousopoulou, A; Garbis, SD; Proud, CG
      The Journal of neuroscience : the official journal of the Society for Neuroscience  35  972-84  2015

      Show Abstract
      Western Blotting25609615 25609615
      Local F-actin network links synapse formation and axon branching.
      Chia, PH; Chen, B; Li, P; Rosen, MK; Shen, K
      Cell  156  208-20  2014

      Show Abstract
      Western Blotting24439377 24439377
      Investigating the role of the actin regulating complex ARP2/3 in rapid ischemic tolerance induced neuro-protection.
      Jessick, VJ; Xie, M; Pearson, AN; Torrey, DJ; Ashley, MD; Thompson, S; Meller, R
      International journal of physiology, pathophysiology and pharmacology  5  216-27  2013

      Show Abstract
      24379906 24379906
      The ARP2/3 complex: giving plant cells a leading edge.
      Mathur, Jaideep
      Bioessays, 27: 377-87 (2005)  2005

      Show Abstract
      15770684 15770684
      Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.
      Steffen, Anika, et al.
      EMBO J., 23: 749-59 (2004)  2004

      Show Abstract
      14765121 14765121
      Control of SCAR activity in Dictyostelium discoideum.
      Blagg, S L and Insall, R H
      Biochem. Soc. Trans., 32: 1113-4 (2004)  2004

      15506982 15506982
      Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.
      Salazar, Marco A, et al.
      J. Biol. Chem., 278: 49031-43 (2003)  2003

      Show Abstract
      14506234 14506234
      Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions.
      Kunda, Patricia, et al.
      Curr. Biol., 13: 1867-75 (2003)  2003

      Show Abstract
      14588242 14588242
      Increased apoptosis induction by 121F mutant p53.
      Saller, E, et al.
      EMBO J., 18: 4424-37 (1999)  1999

      Show Abstract
      10449408 10449408

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