12-516 | Axltide

12-516
1 mg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information
      Description
      Catalogue Number12-516
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAxltide
      References
      Product Information
      PresentationLyophilized powder
      Applications
      Key Applications
      • Kinase Assay
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
      Gene Symbol
      • AXL
      • UFO
      Protein TargetAxl
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P30530 # May function as a signal transducer between specific cell types of mesodermal origin.
      SIZE: 887 amino acids; 97437 Da
      SUBUNIT: Heterodimer and heterotetramer with GAS6.
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      DISEASE:SwissProt: P30530 # Has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia.
      SIMILARITY: SwissProt: P30530 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily. & Contains 2 fibronectin type-III domains. & Contains 2 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by for use as a substrate in protein kinase assay.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Axltide (Axl/Insulin Receptor substrate peptide) 3082824
      Axltide (Axl/Insulin Receptor substrate peptide) 2896061
      Axltide (Axl/Insulin Receptor substrate peptide) 3041075
      Axltide (Axl/Insulin Receptor substrate peptide) - 2193174 2193174
      Axltide (Axl/Insulin Receptor substrate peptide) - 2196199 2196199
      Axltide (Axl/Insulin Receptor substrate peptide) - 2207274 2207274
      Axltide (Axl/Insulin Receptor substrate peptide) - 2297234 2297234
      Axltide - 0703054341 0703054341
      Axltide - 2290365 2290365
      Axltide - 24560 24560

      Related Products & Applications

      Accessories

      Catalogue Number Description  
      14-466 Insulin Receptor Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates
      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates