12-330 | Casein Kinase 2 Substrate Peptide

12-330
1 µmol  
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      Overview

      Replacement Information
      Description
      Catalogue Number12-330
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCasein Kinase 2 Substrate Peptide
      References
      Product Information
      Presentation20 mM MOPS, pH 7.2; 25 mM b-glycerol phosphate; 5 mM EGTA; 1 mM sodium orthovanadate; 1 mM dithiothreitol
      Applications
      ApplicationCasein Kinase 2 Substrate Peptide primarily used in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
      Gene Symbol
      • CSNK2B
      • Phosvitin
      • CK2B
      • CSK2B
      • MGC138224
      • MGC138222
      • CK2N
      • G5a
      • phosvitin
      • G5A
      Protein TargetCK2
      Target Sub-FamilyCMGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P67870 # Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
      SIZE: 215 amino acids; 24942 Da
      SUBUNIT: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
      PTM: Phosphorylated by alpha subunit.
      SIMILARITY: SwissProt: P67870 ## Belongs to the casein kinase 2 subunit beta family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated as a substrate in a kinase assay.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of the product, centrifuge the original vial prior to removing the cap.
      Packaging Information
      Material Size1 µmol
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Certificates of Analysis

      TitleLot Number
      Casein Kinase 2 Substrate Peptide - 0607034940 0607034940
      Casein Kinase 2 Substrate Peptide - 15379 15379
      Casein Kinase 2 Substrate Peptide - 16591 16591
      Casein Kinase 2 Substrate Peptide - 17562 17562
      Casein Kinase 2 Substrate Peptide - 18103 18103
      Casein Kinase 2 Substrate Peptide - 18643 18643
      Casein Kinase 2 Substrate Peptide - 19696 19696
      Casein Kinase 2 Substrate Peptide - 2006547 2006547
      Casein Kinase 2 Substrate Peptide - 2032308 2032308
      Casein Kinase 2 Substrate Peptide - 20668 20668

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates
      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates