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MAB10422 Anti-Plexin-A3 Antibody, clone 18A9.2

Anti-Plexin-A3 Antibody, clone 18A9.2 is a Mouse Monoclonal Antibody for detection of Plexin-A3 also known as PLEXIN-A3, Semaphorin receptor SEX or Plexin-4 & has been validated in WB & IHC.

Anti-Plexin-A3 Antibody, clone 18A9.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: HSSEXGENE, SEX, XAP-6, PLXN3, PLXN4, Plxn3, PLXNA3 UniProt Number: P51805
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MAB10422
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, H, MWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB10422
      DescriptionAnti-Plexin-A3 Antibody, clone 18A9.2
      Alternate Names
      • plexin A3
      • PLEXIN-A3
      • plexin-A3
      • Sex chromosome X transmembrane protein of HGF receptor family 3
      • Semaphorin receptor SEX
      • plexin-4
      • Plexin-4
      Background InformationPlexin-A3 is a cell surface receptor for semaphorin that controls signaling for neuronal axon regulation. Plexin-A3 is thought to play a role in Sema3F and Sema3A signaling, has been described as essential for dorsal turning of the corticospinal tract axons and may be an important contributor to development of hippocampal axonal projections. Plexin-A3 has been found expressed in newly-differentiated sympathetic neurons, but not their neural crest precursors, and together with Plexin-A4, functions cooperatively to regulate the migration of sympathetic neurons and then differentially to guide the sympathetic axons.
      References
      Product Information
      FormatPurified
      Control
      • PC-12 cell lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Plexin-A3 Antibody, clone 18A9.2 is a Mouse Monoclonal Antibody for detection of Plexin-A3 also known as PLEXIN-A3, Semaphorin receptor SEX or Plexin-4 & has been validated in WB & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blot Analysis: 1 µg/mL from a previous lot detected Plexin-A3 on 10 µg of HT-29 and NIH/3T3 cell lysates.

      Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Plexin-A3 in colorectal carcinoma tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Plexin-A3.
      Clone18A9.2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Rat
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the plexin class of proteins. The encoded protein is a transmembrane protein that is exposed on the cell surface. This gene is thought to be involved in epithelial and neural tissue development. [provided by RefSeq].
      Gene Symbol
      • HSSEXGENE
      • SEX
      • XAP-6
      • PLXN3
      • PLXN4
      • Plxn3
      • PLXNA3
      Purification MethodProtein G
      UniProt Number
      UniProt SummaryFUNCTION: Putative receptor involved in the development of neural and epithelial tissues.

      SUBCELLUALR LOCATION: Membrane; Single-pass type I membrane protein (Potential).

      TISSUE SPECIFICTY: Predominant in neural tissue during development (By similarity); widely expressed in adult tissue.

      SEQUENCE SIMILARITIES: Belongs to the plexin family.

      Contains 4 IPT/TIG domains.

      Contains 1 Sema domain.
      Molecular Weight~220 kDa observed. The calculated molecular weight of this protein is 208 kDa; however, a higher band may be observed due to glycosolation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in PC-12 cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected Plexin-A3 on 10 µg of PC-12 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB10422 04053252749544

      Documentation

      Anti-Plexin-A3 Antibody, clone 18A9.2 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Plexin-A3 Antibody, clone 18A9.2 Certificates of Analysis

      TitleLot Number
      Anti-Plexin-A3, clone 18A9.2 - 2115671 2115671
      Anti-Plexin-A3, clone 18A9.2 - 2370170 2370170
      Anti-Plexin-A3, clone 18A9.2 - 2381785 2381785
      Anti-Plexin-A3, clone 18A9.2 - 2428363 2428363
      Anti-Plexin-A3, clone 18A9.2 - 2436815 2436815
      Anti-Plexin-A3, clone 18A9.2 - 3286442 3286442
      Anti-Plexin-A3, clone 18A9.2 - 3906477 3906477
      Anti-Plexin-A3, clone 18A9.2 - NRG1845787 NRG1845787
      Anti-Plexin-A3, clone 18A9.2 -2893206 2893206
      Anti-Plexin-A3, clone 18A9.2 Monoclonal Antibody 2919609