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MAB4416 Anti-Plet-1 (Placenta-expressed transcript 1 protein) Antibody, clone 1D4

This Anti-Plet-1 (Placenta-expressed transcript 1 protein) Antibody, clone 1D4 is validated for use in WB, IC, IH, FC for the detection of Plet-1 (Placenta-expressed transcript 1 protein).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: PLET1, C11orf34 UniProt Number: Q6UQ28
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MAB4416
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, ICC, IHC, FCRPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB4416
      DescriptionAnti-Plet-1 (Placenta-expressed transcript 1 protein) Antibody, clone 1D4
      Alternate Names
      • chromosome 11 open reading frame 34
      • hypothetical protein LOC349633
      • placenta expressed transcript 1
      Background InformationPlacenta-expressed transcript-1 (Plet-1) is a recently identified protein that as of yet has no known function and is not associated with any one family of proteins. Its observation has been restricted to developing mesonephros and pharyngeal endoderm. Observation in adult tissue is more widely expressed, having been found in several locations such as mammary, pancreas and prostate epithelia. Its location in the pancreas is notable as the pancreas is a well known reserve for stem cells and progenitor cells. Within the pancreas, Plet-1 has been shown to be localized in the major duct epithelium, and as such will serve as an excellent marker for epithelial progenitor cells and stem cells, and as a useful implement for observing the genetics of linear relationships and the operation of molecular mechanisms for homeostasis, development and wound healing in organ and tissue systems.
      Recently, Plet-1 has been identified as a specific marker of early thymic epithelial progenitor cells. In the postgastrulation embryo, Plet-1 expression is highly restricted to the developing pharyngeal endoderm and mesonephros. This antibody recognizes the same protein as MTS20 and MTS24.
      References
      Product Information
      FormatPurified
      Control
      • Human placenta cell lysate
      PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Plet-1 (Placenta-expressed transcript 1 protein) Antibody, clone 1D4 is validated for use in WB, IC, IH, FC for the detection of Plet-1 (Placenta-expressed transcript 1 protein).
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: A previous lot was used by an independent laboratory in FC (Depreter, M.G.L., et al., 2008).

      Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH (Depreter, M.G.L., et al., 2008).

      Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Depreter, M.G.L., et al., 2008).
      Biological Information
      ImmunogenFull length recombinant protein corresponding to Plet-1.
      EpitopeUnknown
      Clone1D4
      HostRat
      SpecificityThis antibody recognizes Plet-1.
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      • Mouse
      Species Reactivity NoteDemonstrated to react with human.
      Predicted to react with mouse based on 100% sequence homology.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PLET1
      • C11orf34
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: May participate in the wound response during the healing process, and promote wound repair.

      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein Potential.
      Molecular Weight~ 23 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human placenta cell lysate.

      Western Blot Analysis: A 1:2,500 dilution of this antibody detected Plet-1 in 10 µg of human placenta cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB4416 04053252478505

      Documentation

      Anti-Plet-1 (Placenta-expressed transcript 1 protein) Antibody, clone 1D4 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Plet-1 (Placenta-expressed transcript 1 protein) Antibody, clone 1D4 Certificates of Analysis

      TitleLot Number
      Anti-Plet-1, clone 1D4 2476963
      Anti-Plet-1, clone 1D4 - 2145981 2145981
      Anti-Plet-1, clone 1D4 - 1967287 1967287
      Anti-Plet-1, clone 1D4 - 2283913 2283913
      Anti-Plet-1, clone 1D4 - 3234530 3234530
      Anti-Plet-1, clone 1D4 - 3385824 3385824
      Anti-Plet-1, clone 1D4 - 3792966 3792966
      Anti-Plet-1, clone 1D4 - 3862685 3862685
      Anti-Plet-1, clone 1D4 - 3958866 3958866
      Anti-Plet-1, clone 1D4 - 4061191 4061191
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      Data Sheet

      Title
      Reprogramming Cell Fate and Function Novel Strategies for iPSC Generation, Characterization, and Differentiation