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MABS499 Anti-Phosphothreonine Antibody, clone RM102

Anti-Phosphothreonine, clone RM102 is an antibody against Phosphothreonine for use in WB, ICC, IH, IP.

Anti-Phosphothreonine Antibody, clone RM102 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: General Post-translation Modification Gene Symbol: N/A
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MABS499
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IHC, IPRbAffinity PurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS499
      DescriptionAnti-Phosphothreonine Antibody, clone RM102
      Alternate Names
      • p-Thr
      • pthr
      • phospho-threonine
      Background InformationProtein phosphorylation and dephosphorylation are basic mechanisms for the modification of protein function in eukaryotic cells. Phosphorylation is a rare post-translational event in normal tissue, however, the abundance of phosphorylated cellular proteins increases several fold following various activation processes which are mediated through phosphotyrosine, phosphoserine or phosphothreonine (p-tyr/p-ser/p-thr). Many signal transduction pathways, such as the EGF, PDGF and insulin receptor systems, contain tyr/ser/thr kinase which phosphorylate specific tyr/ser/thr residues upon binding of ligands to their receptors. T cell antigen receptor complex or the receptors for some hemopoietic growth factors may stimulate these phosphorylation associated kinases, and cells transformed by viral oncogenes contain elevated levels of phosphorylated tyr/ser/thr.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit monoclonal IgG in PBS buffer containing 1% BSA and 0.09% sodium azide
      Quality LevelMQ100
      Applications
      ApplicationAnti-Phosphothreonine, clone RM102 is an antibody against Phosphothreonine for use in WB, ICC, IH, IP.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      • Immunoprecipitation
      Application NotesImmunocytochemistry Analysis: A representative lot of this antibody at 1:500 dilution detected phosphothreonine modification on Calyculin A/Okadaic Acid treated A431 cells
      Immunohistochemistry Analysis: A representative lot of this antibody at 1:500 dilution detected phosphothreonine modification on human colon cancer tissue
      Immunoprecipitation Analysis: A representative lot of this antibody at 1:500 dilution immunoprecipitated phosphothreonine modified proteins from Calyculin A/Okadaic Acid treated A431 cell lysate
      Biological Information
      ImmunogenMix of recombinant protein and peptide corresponding to All Phosphothreonine.
      CloneRM102
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      Species Reactivity NoteHuman, Predicated to react with all species
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • N/A
      Purification MethodProtein A Purfied
      Molecular WeightN/A kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting on Calyculin A/Okadaic Acid treated HeLa cell lysate

      Western Blotting Analysis: A 1:2000 dilution of this antibody detected phosphothreonine modification on Calyculin A/Okadaic Acid treated HeLa cell lysate
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS499 04055977115949

      Documentation

      Anti-Phosphothreonine Antibody, clone RM102 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Phosphothreonine Antibody, clone RM102 Certificates of Analysis

      TitleLot Number
      Anti-Phosphothreonine, clone RM102 QVP1406134
      Anti-Phosphothreonine, clone RM102 - VP1912274 VP1912274
      Anti-Phosphothreonine, clone RM102 - VP210853 VP210853
      Anti-Phosphothreonine, clone RM102 - VP2501291 VP2501291
      Anti-Phosphothreonine, clone RM102 -QVP1504078 QVP1504078
      Anti-Phosphothreonine, clone RM102 -VP1509034 VP1509034
      Anti-Phosphothreonine, clone RM102 -VP1603020 VP1603020
      Anti-Phosphothreonine, clone RM102 Monoclonal Antibody VP1809280
      Anti-Phosphothreonine, clone RM102 Monoclonal Antibody VP1701201