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PC56 Anti-MLH1 (Ab-2) Rabbit pAb

This Anti-MLH1 (Ab-2) Rabbit pAb is validated for use in Immunoblotting for the detection of MLH1 (Ab-2).

Anti-MLH1 (Ab-2) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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PC56
  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      H, MRbPolyclonal Antibody
      Description
      OverviewRecognizes the ~83 kDa MLH1 protein.
      Catalogue NumberPC56
      Brand Family Calbiochem®
      References
      ReferencesBronner, C.E., et al. 1994. Nature 368, 258.
      Papadopoulos, N., et al. 1994. Science 263, 1625.
      Peltomäki, P.T. 1994. Ann. Med. 26, 215.
      Fishel, R., et al. 1993. Cell 75, 1027.
      Leach, F.S., et al. 1993. Cell 75, 1215.
      Lindbolm, A., et al. 1993. Nat. Genet. 5, 279.
      Product Information
      FormLiquid
      FormulationIn 0.05 M sodium phosphate buffer, 0.2% gelatin.
      Negative controlHCT116 cells
      Positive controlLoVo cells
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1 µg/ml)
      Application CommentsAntibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogenrecombinant human MLH1
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Yes
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      PC56 0

      Documentation

      Anti-MLH1 (Ab-2) Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-MLH1 (Ab-2) Rabbit pAb Certificates of Analysis

      TitleLot Number
      PC56

      References

      Reference overview
      Bronner, C.E., et al. 1994. Nature 368, 258.
      Papadopoulos, N., et al. 1994. Science 263, 1625.
      Peltomäki, P.T. 1994. Ann. Med. 26, 215.
      Fishel, R., et al. 1993. Cell 75, 1027.
      Leach, F.S., et al. 1993. Cell 75, 1215.
      Lindbolm, A., et al. 1993. Nat. Genet. 5, 279.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-October-2007 RFH
      ApplicationImmunoblotting (1 µg/ml)
      DescriptionPurified rabbit polyclonal antibody. Recognizes the ~83 kDa MLH1 protein.
      BackgroundThe MLH1 gene is one of at least 4 genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MLH1 gene contribute to the development of sporadic colorectal carcinoma, while germline MLH1 mutations are responsible for approximately 35% of inherited, non-polyposis colorectal carcinoma (HNPCC). MLH1 encodes a protein of 756 amino acids.
      HostRabbit
      Immunogen speciesHuman
      Immunogenrecombinant human MLH1
      IsotypeIgG
      Specieshuman, mouse
      Positive controlLoVo cells
      Negative controlHCT116 cells
      FormLiquid
      FormulationIn 0.05 M sodium phosphate buffer, 0.2% gelatin.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsAntibody should be titrated for optimal results in individual systems.
      Storage +2°C to +8°C
      Do Not Freeze Yes
      Toxicity Standard Handling
      ReferencesBronner, C.E., et al. 1994. Nature 368, 258.
      Papadopoulos, N., et al. 1994. Science 263, 1625.
      Peltomäki, P.T. 1994. Ann. Med. 26, 215.
      Fishel, R., et al. 1993. Cell 75, 1027.
      Leach, F.S., et al. 1993. Cell 75, 1215.
      Lindbolm, A., et al. 1993. Nat. Genet. 5, 279.