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S8005M CpGenome™ 5-mC DNA Standard

This standard can be used to calibrate applications aimed at analyzing & quantifying cytosine modifications.

CpGenome™ 5-mC DNA Standard MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
S8005M
2 µg per vial  
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      Overview

      Replacement Information
      Description
      Catalogue NumberS8005M
      Brand Family Upstate
      Trade Name
      • CpGenome
      • Upstate
      DescriptionCpGenome™ 5-mC DNA Standard
      OverviewCpGenome™ 5-mC DNA Standard is a linear, double-stranded DNA (897 bp) containing 100% 5-methylcytosine. This standard can be used to calibrate applications aimed at analyzing and quantifying cytosine modifications. This vial is a component of S8005 the CpGenome™ 5-mC and 5-hmC DNA Standard Set ( three linear, double-stranded DNAs (897 bp) with the same sequence, but containing either 100% 5-Methylcytosines (5-mC), 5-hydroxymethylcytosines (5-hmC), or unmodified cytosines.

      Materials Provided:

      One vial containing 2 µg (40 µL) of CpGenome™ 5-mC DNA Standard at a concentration of 50 ng/μL.

      Validation:

      Standards containing either 5-mC, 5-hmC, or unmodified cytosines were digested with 1 µL (20 units) of HpaII (which cleaves only unmethylated DNA), or PvuRts1I restriction enzyme (which targets only 5-hydroxymethylated DNA). The resulting DNA fragments were evaluated by agarose gel electrophoresis.

      CpGenome is a trademark of Serologicals Corporation.
      References
      Product Information
      PresentationLiquid in buffer containing 10 mM Tris-HCl, 1 mM EDTA, pH 8.0
      Quality LevelMQ300
      Applications
      ApplicationThis standard can be used to calibrate applications aimed at analyzing & quantifying cytosine modifications.
      Biological Information
      Species Reactivity
      • Human
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsRecommended Storage: Stable for 6 months at -20°C from date of receipt.
      Packaging Information
      Material Size2 µg per vial
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      S8005M 04053252908941