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14-195M c-Jun (1-169)-GST Protein, soluble, 250 µg

250 μg of c-Jun (1-169)-GST, soluble, N-terminal, Glutathione-Stransferase (GST) tagged, fusion protein, for use in Kinase Assays.

14-195M
250 µg  Also available in 100 μg size (cat#14-195) and in bulk (cat#14-195-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-195M
      Brand Family Upstate
      Trade Name
      • Upstate
      Descriptionc-Jun (1-169)-GST Protein, soluble, 250 µg
      OverviewN-terminal, Glutathione-Stransferase (GST) tagged, fusion protein
      References
      Product Information
      Quality LevelMQ300
      Applications
      Application250 μg of c-Jun (1-169)-GST, soluble, N-terminal, Glutathione-Stransferase (GST) tagged, fusion protein, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourcecorresponding to truncated human c-Jun (1-169) expressed in E. coli
      Entrez Gene Number
      Entrez Gene SummaryThis gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
      Gene Symbol
      • JUN
      • AP1
      • p39
      • c-Jun
      Protein Targetc-Jun
      Purification MethodGlutathione agarose affinity chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P05412 # Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
      SIZE: 331 amino acids; 35676 Da
      SUBUNIT: Interacts with FOS to form a dimer. Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.
      SUBCELLULAR LOCATION: Nucleus.
      PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC.
      SIMILARITY: SwissProt: P05412 ## Belongs to the bZIP family. Jun subfamily. & Contains 1 bZIP domain.
      Molecular Weight41 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of GST
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -20 C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 100 μg size (cat#14-195) and in bulk (cat#14-195-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-195M 04053252924040

      Documentation