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855035 DFPE polystyrene

Overview

Replacement Information

Key Spec Table

CAS #
9003-70-7
Description
Catalogue Number855035
Replaces01-64-0360
Brand Family Novabiochem®
Alternate Names
  • 2-(3,5-Dimethoxy-4-formylphenoxy)ethyl polystyrene
Background InformationThis resin is prepared under conditions optimized to minimize styrene formation during attachment of the linker to the functionalized ethylpolystyrene support. This high substitution, coupled with the lack of amide bonds and potentially acid-sensitive benzylic linkages, makes this support the preferred choice of SPOS of secondary sulfonamides and carboxamides. Applications of FMPE include aminofurazanopyrazines [1] and peptide agonists for human orphan receptor BRS-3 [2].

The product number for this product was previously 01-64-0360.

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References
Product Information
CAS number9003-70-7
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to red
Appearance of substance (visual)beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide)0.50 - 1.10 mmol/g
Swelling Volume (in DMF)lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 100 -200 mesh

Documentation

DFPE polystyrene SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] B. Dörner & P. White in 'Peptides 1998, Proc. 25th European Peptide Symposium', S. Bajusz & F. Hudecz (Eds), Budapest, Akadémiai Kiadó, 1999, pp. 90.
  • [2] M. Grimstrup & F. Zaragoza (2002) Eur. J. Org. Chem., 2953.
  • [3] K. J. Jensen, et al. (1998) J. Am. Chem. Soc., 120, 5441.
  • [4] M. del Fresno, et al. (1998) Tetrahedron Lett., 39, 2639.
  • [5] N. S. Gray, et al. (1997) Tetrahedron Lett., 38, 1161.
  • [6] J. Alsina, et al. (1999) Chem. Eur. J., 5, 2787.
  • [7] J. F. Tolborg & K. J. Jensen (2000) Chem. Commun., 147.
  • [8] A. E. Fenwick, et al. (2001) Bioorg. Med. Chem. Lett., 11, 195.
  • [9] J. Giovannoni, et al. (2001) Tetrahedron Lett., 42, 5389.
  • [10] J. T. Bork, et al. (2003) Org. Lett., 5, 117.
  • [11] C. P. Holmes, Paper ORGN 383 presented at the 213th National Meeting of the American Chemical Society, San Francisco, 1997.
  • [12] C. Pégurier, et al. (2000) Bioorg. Med. Chem., 8, 163.
  • [13] T. F. Herpin, et al. (2000) J. Comb. Chem., 2, 513.