344154
FPT Inhibitor III
(E,E)-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester, Na
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Faks: +49 6151 72 2000
31 May 2012
memuat
A cell-permeable prodrug ester form of farnesyltransferase (FTase) inhibitor II (Cat. No. 344152). Also inhibits Ras processing in cells (~100 µM), thereby preventing Ras-mediated transformation. Inhibits C15 and C20 protein prenylation in NIH-3T3 cells.
| Informasi produk | |||
|---|---|---|---|
| Form | Pale yellow solid | ||
| Primary Target | FTase | ||
| Primary Target IC50 | 75 nM | ||
| Secondary target | Ras processing in cells | ||
| Hygrocopic | Ya | ||
| Cell permeable | Ya | ||
| Purity | ≥90% by HPLC | ||
| Formulasi kimia | C23H39NO7P . Na | ||
| Simpan dan kirim informasi | |||
|---|---|---|---|
| Penyimpanan | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
