344510
FTase Inhibitor I
N-[2(S)-[2(R)-Amino-3-mercaptopropylamino]-3-methylbutyl]-Phe-Met-OH, B581
Untuk pertanyaan umum, silakan hubungi Layanan Pelanggan kami:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Faks: +49 6151 72 2000
31 May 2012
memuat
A potent, cell-permeable, selective, peptidomimetic inhibitor of farnesyltransferase (FTase) that is approximately 37-fold more active against FTase (IC50 = 21 nM in vitro) than against geranylgeranyltransferase (GGTase; IC50 = 790 nM). Very resistant to proteolysis.
| Informasi produk | |||
|---|---|---|---|
| Form | White solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Primary Target | FTase | ||
| Primary Target IC50 | 21 nM in vitro | ||
| Secondary target | GGTase (IC50 = 790 nM) | ||
| Hygrocopic | Ya | ||
| Packaged under inert gas | Ya | ||
| Cell permeable | Ya | ||
| Purity | ≥90% by HPLC | ||
| Formulasi kimia | C22H38N4O3S2 | ||
| Simpan dan kirim informasi | |||
|---|---|---|---|
| Penyimpanan | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
