104551
ACC2 Inhibitor, CD-017-0191
2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine
ご質問については、カスタマーサービスまでご連絡ください。
メルク株式会社
目黒区下目黒1-8-1
153-8927 東京
Japan
TEL： 0120-189-390
Fax: 0120-189-350
E-mail mj_service@merckgroup.com
31 5月 2012
ローディング
A cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC50 = 2.8 µM), which does not inhibit human ACC1 at all at concentrations up to 100 µM, in vitro. It is also shown to inhibit the growth of yeast (IC50 = 3.8 µM), in which the native ACC1 gene is replaced with the human ACC2 strain; but not with the human ACC1 strain at concentrations ≤ 100 µM. This compound is not demonstrated to be toxic to human cells in culture at concentrations up to 10 µM.
| 製品情報 | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Purity | ≥90% by HPLC | ||
| 化学式 | C20H19N3O3S | ||
| 保管と送付情報 | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
