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345744 Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem

Inhibits Con A-stimulated mitogenesis in murine T cells.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Neu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄

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345744
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₉₅H₁₆₂N₅O₄₇ · 3NH₄

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      		 Plastic ampoule 1 mg
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      Description
      OverviewInhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.
      M.W. 2180.5 (based on stearoyl - 18:0).
      Catalogue Number345744
      Brand Family Calbiochem®
      SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
      References
      ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
      Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
      Warren, L. 1959. J. Biol. Chem. 234, 1971.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      Hill FormulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
      Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetInhibits Con A-stimulated mitogenesis in murine T cells
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      345744-1MG 04055977193862

      Documentation

      Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem Certificates of Analysis

      TitleLot Number
      345744

      References

      Reference overview
      Hakomori, S. 1985. Cancer Res. 45, 2405.
      Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
      Warren, L. 1959. J. Biol. Chem. 234, 1971.

      Brochure

      Title
      Gangliosides Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-July-2009 JSW
      SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
      DescriptionTrisialoganglioside prepared from bovine gray matter. Readily converted to GD1b-disialoganglioside by bacterial and mammalian sialidases without detergent or bile salts. Inhibits mitogenesis in concanavalin A-stimulated murine T-cells. Lymphocyte marker in cancer patients.

      Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
      FormLyophilized
      Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityEthanol or Methanol. For use in aqueous systems, dissolve in a small amount of ethanol and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions can be filter sterilized.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
      Toxicity Irritant
      ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
      Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
      Warren, L. 1959. J. Biol. Chem. 234, 1971.