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855049 H-Thr-Gly-NovaSyn® TG resin

Overview

Replacement Information
Description
Catalogue Number855049
Replaces04-12-3710
Brand Family Novabiochem®
Background InformationThis resin is a useful tool for the synthesis of peptide aldehydes [1]. Attachment of pre-formed amino acid aldehydes to this resin is effected by heating in 1% DIPEA in MeOH at 60 °C. Following chain extension using standard protocols, side-chain protecting groups can be removed with anhydrous TFA, prior to cleavage of the fully deprotected peptide aldehyde with MeCN/water/TFA.

An analogous resin has been recently used to capture and purify peptide aldehydes generated by oxidation of peptide alcohols with IBX-polystyrene [2].

Novabiochem's pre-loaded amino aldehyde resins can be found on page x.

The product number for this product was previously 04-12-3710.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc- Oxybenzaldehyde loaded resin)0.15 - 0.35 mmol/g
Identity (of the substitution)passes test
Swelling Volume (in DMF)lot specific result
The base resin is amino PEG-PS-copolymer (90 µm).

Documentation

H-Thr-Gly-NovaSyn® TG resin SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] N. J. Ede, et al. (2000) J. Peptide Sci., 6, 11.
  • [2] G. Sorg, et al. (2005) J. Peptide Sci., 11, 142.