176708
Angiostatin K1-3, Human, Recombinant, E. coli
Ang K1-3, K1-3, rHuAng K1-3
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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Recombinant, human angiostatin expressed in E. coli as a single, nonglycosylated polypeptide chain containing 259 amino acids. Represents a proteolytic fragment containing the first three kringle structures of plasminogen. Acts as a specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50=70 nM) relative to kringles 1-4 (ED50=135 nm).
| Product information | |||
|---|---|---|---|
| Form | Lyophilized powder | ||
| Formulation | Lyophilized from 20 mM Sodium Acetate, 4% Mannitol, pH 5.5. | ||
| Molar mass | 30000 | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥95% by HPLC and SDS-PAGE | ||
| Solubility | H2O or Aqueous Buffer Containing 0.1% BSA | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Blue Ice Only
Standard Handling |
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