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422751 Anti-ADAM10 (735-749) Rabbit pAb

Anti-ADAM10 (735-749) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Kuz

422751
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.



      We apologize for the inconvenience, but we do not currently have an alternative product.






      Recognizes the ~98 and ~105 kDa bands corresponding to full length ADAM1O in transfected CHO-K cells, the ~60 kDa cleaved mature protein and the ~30 kDa degradation product.
    • Antibody Target Gene Symbol: ADAM10
    • Target Synonym: 1700031C13Rik, AD10, ALPHA SECRETASE, CD156c, DISINTEGRIN-METALLOPROTEASE, HsT18717, Kuz, KUZBANIAN, MADM
    • Entrez Gene Name: ADAM metallopeptidase domain 10
    • Hu Entrez ID: 102 (Related Antibodies: PC528)
    • Mu Entrez ID: 11487
    • Rat Entrez ID: 29650
      		•
      Catalogue Number422751
      Brand Family Calbiochem®
      SynonymsAnti-Kuz
      References
      ReferencesQi, H., et al. 1999. Science 283, 91.
      Pan, D. and Rubin, G.M. 1997. Cell 90, 271.
      Rosendahl, M.S., et al. 1997. J. Biol. Chem. 272, 24588.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      Positive controlADAM10-transfected CHO cells
      PreservativeNone
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1:2000)
      Application CommentsVariables associated with assay conditions will dictate the optimal working dilution.
      Biological Information
      Immunogena synthetic peptide [(C)RQRPRESYQMGHMRR] corresponding to amino acids 735-749 of mouse ADAM10
      ImmunogenMouse
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      422751 0

      Documentation

      References

      Reference overview
      Qi, H., et al. 1999. Science 283, 91.
      Pan, D. and Rubin, G.M. 1997. Cell 90, 271.
      Rosendahl, M.S., et al. 1997. J. Biol. Chem. 272, 24588.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-October-2007 JSW
      SynonymsAnti-Kuz
      ApplicationImmunoblotting (1:2000)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~98 and ~105 kDa bands corresponding to full length ADAM10, the ~60 kDa cleaved mature protein, and the ~30 kDa degradation product.
      BackgroundKUZ (ADAM10) is a disintegrin metallo-protease in the family of mammalian ADAM. ADAM10 was recently demonstrated to cleave TNFα, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated as ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
      HostRabbit
      Immunogen speciesMouse
      Immunogena synthetic peptide [(C)RQRPRESYQMGHMRR] corresponding to amino acids 735-749 of mouse ADAM10
      IsotypeIgG
      Specieshamster, human, mouse
      Positive controlADAM10-transfected CHO cells
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the optimal working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesQi, H., et al. 1999. Science 283, 91.
      Pan, D. and Rubin, G.M. 1997. Cell 90, 271.
      Rosendahl, M.S., et al. 1997. J. Biol. Chem. 272, 24588.