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31 May 2012
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Recombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.
M.W. 23,000 (monomer); 115,000 (pentamer).
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 140 mM NaCl, 20 mM Tris-HCl, 2 mM CaCl2, 0.05% NaN3, pH 7.5. | ||
| Do not freeze | Yes | ||
| Purity | single band by SDS-PAGE | ||
| Solubility | Aqueous buffers | ||
| CAS number | 9007-41-4 | ||
| Merck USA index | 14, 2603 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Blue Ice Only
Standard Handling |
||
