216201
Carboxyatractyloside, Potassium Salt, Xanthium sibiricum
C-ATR, CAT
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31 May 2012
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Toxic compound isolated from the plant Xanthium sibiricum. A highly selective and potent inhibitor of adenine nucleotide translocator (ANT) (Ki < 10 nM) and inducer of permeability transition pore opening. Stabilizes the nucleoside binding site of ANT on the cytoplasmic side of the inner membrane and blocks the exchange of matrix ATP and cytoplasmic ADP. Does not affect the activity of mitochondrial multiple conductance channel (MCC).
CAS No. refers to that of the free acid.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Molar mass | 939.1 | ||
| Protect from Moisture | Yes | ||
| Hygrocopic | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | H2O | ||
| Chemical formula | C31H43O18S2K3•3H2O | ||
| CAS number | 35988-42-2 | ||
| Store and ship information | |||
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Toxic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36/37-45 Wear suitable protective clothing and gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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| R Phrase |
R: 23/24/25 Toxic by inhalation, in contact with skin and if swallowed. |
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