400025
Caspase-1 Substrate IV, Colorimetric
IL-1β Converting Enzyme (ICE) Colorimetric Substrate, Ac-YVAD-pNA
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Colorimetric caspase-1 substrate that is similar in sequence to Caspase-1 Substrate III, Fluorogenic (Cat. No. 400020). Cleavage of pNA is monitored colorimetrically at ~405 nm (ε = 9,160 M-1cm-1). Sequence is based on the caspase-1 cleavage site of the IL-1β precursor and includes Asp116. Also a substrate for caspase-4.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | Ac-Tyr-Val-Ala-Asp-pNA | ||
| Form | Lyophilized | ||
| Molar mass | 628.6 | ||
| Protect from Light | Yes | ||
| Protect from Moisture | Yes | ||
| Purity | ≥95% by HPLC | ||
| Sold on the basis of peptide content | Yes | ||
| Solubility | DMSO | ||
| Chemical formula | C29H36N6O10 | ||
| CAS number | 149231-66-3 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
