218775
Castanospermine, Castanospermum australe
(1S,6S,7R,8aR)-Tetrahydroxyoctahydroindolizine
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
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31 May 2012
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Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. Resulting oligosaccharides are primarily Glu3Man7-9(GlcNAc)2. Reduces bFGF induced angiogenesis in mice. Inhibits endothelial cell migration and invasion of basement membrane. Exhibits anti-viral properties. Typically used at 1-10 µg/ml.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Primary Target | β-glucosidases | ||
| Molar mass | 189.2 | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by TLC | ||
| Solubility | H2O | ||
| Chemical formula | C8H15NO4 | ||
| CAS number | 79831-76-8 | ||
| Merck USA index | 14, 1896 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
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| R Phrase |
R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
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