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31 May 2012
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Native cathepsin D from bovine spleen. Cathepsin D is a major lysosomal aspartyl proteinase widely distributed in many cell types. It exists in two forms, a single polypeptide chain of 46 kDa, and a two-polypeptide chain form consisting of an H-chain of 34 kDa and an L-chain of 12 kDa.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Formulation | Lyophilized from 2 mM sodium phosphate buffer, pH 6.5. | ||
| Molar mass | 46000 | ||
| Specific activity | ≥400 units/mg protein | ||
| Unit definition | One unit is defined as the amount of enzyme that will digest acid-denatured hemoglobin in 30 minutes, at 37°C, pH 3.3, releasing peptides soluble in TCA, as measured by an increase in absorbance of 0.5 at 280 nm. | ||
| Purity | ≥95% by SDS-PAGE | ||
| Solubility | H2O or 2 mM Sodium Phosphate Buffer, pH 6.5 | ||
| EC number | 3.4.23.5 | ||
| CAS number | 9025-26-7 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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