220201
CHAPS, Molecular Biology Grade
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than structurally-related carboxylic acid anions and is much more effective at breaking protein-protein interactions than either sodium cholate or TRITON® X-100 Detergent. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Also, capable of disaggregating cytochrome P450 to its monomeric form without denaturation. Has a small micellar molecular weight and a high critical micellar concentration and can be removed from either gels or protein solutions by dialysis across a membrane. Aggregation number: 4-14.
Conductivity (1.0 M, 24°C): <100 µmhos.
| Product information | |||
|---|---|---|---|
| Form | White crystalline powder | ||
| Molar mass | 614.9 | ||
| Hygrocopic | Yes | ||
| Purity | ≥98% by TLC | ||
| Contaminants | DNase, RNase, and Protease: none detected | ||
| Aggregation Number | 4 - 14 | ||
| CMC | 6 - 10 mM | ||
| Micellar weight | 6150 | ||
| Solubility | H2O | ||
| Chemical formula | C32H58N2O7S | ||
| CAS number | 75621-03-3 | ||
| Merck USA index | 14, 2044 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Harmful |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
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| R Phrase |
R: 22-36/38 Harmful if swallowed. Irritating to eyes and skin. |
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