219365
Coagulation Factor V, Human Plasma
Proaccelerin, Labile Factor, Ac-globulin, Ac-g
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors that form a "prothrombinase" complex with Factor X, enabling its proteolytic activation of prothrombin to thrombin.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 50% glycerol/H2O (v/v). | ||
| Molar mass | 300000 | ||
| Specific activity | ≥20 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma | ||
| Purity | ≥95% by SDS-PAGE | ||
| Source | Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| CAS number | 9001-24-5 | ||
| Merck USA index | 14, 3919 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Blue Ice Only
Standard Handling |
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