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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Native coagulation factor VIIa from human plasma prepared from human Factor VII using human Factor XIIa, which was removed after activation. In the coagulation process, after complexing with tissue factor and membrane phospholipids, Factor VIIa activates Factors IX and X to the enzymatically active Factors IXa and Xa. Provides a crossover point between the extrinsic and intrinsic pathways.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 100 mM NaCl, 20 mM Tris-HCl, pH 7.5. | ||
| Molar mass | 48000 | ||
| Avoid freeze/thaw | Yes | ||
| Specific activity | ≥25,000 PEU/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma | ||
| Purity | ≥95% by SDS-PAGE | ||
| Source | Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| EC number | 3.4.21.21 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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