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31 May 2012
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Recombinant, human cytochrome b5 expressed in E. coli. A membrane-bound hemoprotein that enhances the catalytic efficiency of some P450 isoforms, most notably members of the 3A subfamily. Serves as an electron buffer and is speculated to play either a direct role in electron transfer or an indirect role through allosteric interactions with P450. Suitable for in vitro drug metabolism and toxicology studies including reconstituted P450-dependent biotransformation reactions.
Heme content: ≥60 nmol/mg protein.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 20 mM sodium/potassium phosphate buffer, 100 µM EDTA, pH 7.25. | ||
| Molar mass | 14000 | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥90% by SDS-PAGE | ||
| CAS number | 9078-32-4 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
