574215
D,L-Sulforaphane
1-Isothiocyanato-4-(methylsulfinyl)butane, R,S-Sulforaphane
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Merck KGaA
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Fax: +49 6151 72 2000
24 May 2012
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An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture. It has been shown to be an effective agent in prevention of chemically-induced mammary tumors in rats. It also inhibits the phase I cytochrome P450 isoenzymes 2E1 and IA2 which have been associated with the activation of carcinogens. The induction of phase II enzymes is mediated by mitogen-activated protein kinase (MAPK) pathway.
| Product information | |||
|---|---|---|---|
| Form | Slight yellow liquid | ||
| Molar mass | 177.3 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by UPLC | ||
| Solubility | DMSO or EtOH | ||
| Chemical formula | C6H11NOS2 | ||
| CAS number | 4478-93-7 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
