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01 June 2012
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Native elastase from human neutrophil. A serine protease that degrades elastin, collagen, and proteoglycans. Its overexpression has been implicated in the development of pulmonary emphysema, rheumatoid arthritis, and cystic fibrosis.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized solid | ||
| Formulation | Salt-free. | ||
| Molar mass | 29500 | ||
| Specific activity | ≥20 units/mg protein. | ||
| Unit definition | One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol of MeO-Suc-Ala-Ala-Pro-Val-pNA (Cat. No. 454454) per min at 25°C, pH 8.0. | ||
| Purity | Major band by SDS-PAGE | ||
| Source | Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| Solubility | Aqueous Buffers | ||
| EC number | 3.4.21.37 | ||
| RTECS | JX7069000 | ||
| CAS number | 9004-06-2 | ||
| Merck USA index | 14, 3535 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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