324693  Emetine, Dihydrochloride

6′,7′,10,11-Tetramethoxyemetan, 2HCl

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18 April 2014

Product number Qty/Pk Quantity Price
324693-250MG  250 mg  loading
Prices are subject to change without notice.
Principal alkaloid of ipecac, isolated from the ground roots of Uragoga ipecacuanha. Irreversibly blocks protein synthesis in eukaryotes by inhibiting the movement of ribosomes along the mRNA. Induces hypotension by blocking adrenoreceptors. Interferes with cytometric analysis of DNA replication at the early S phase. Also identified as a specific inhibitor of HIF-2α protein stability and transcriptional activity (IC50 ≤1 µM.
Product information
Form White solid with a faint yellow cast
Primary Target movement of ribosomes along the mRNA
Molar mass 553.6
Protect from Light Yes
Hygrocopic Yes
Purity ≥98% by HPLC and Titration (dried basis) (perchloric acid method)
Solubility EtOH or H2O
Chemical formula C29H40N2O4 · 2HCl
RTECS JY5250000
CAS number 316-42-7
Merck USA index 14, 3559
Store and ship information

Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Storage +2°C to +8°C
Ship Ambient Temperature Only
Highly Toxic
Safety information
S Phrase S: 28-36/37-45

Wear suitable protective clothing and gloves.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
R Phrase R: 28-36/38

Very toxic if swallowed.
Irritating to eyes and skin.
Emetine, Dihydrochloride, molecular structure

© Merck KGaA, Darmstadt, Germany, 2014


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