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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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Highly specific for divalent cations and more effective than A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G1 phase in mature Burkitt lymphoma cell lines.
Absorption max. (280 nm, MeOH): 18,600 M-1cm-1.
| Alternatives | |
|---|---|
| 407952 | Ionomycin, Calcium Salt, Streptomyces conglobatus |
| Alternative products for Ionomycin, Free Acid, Streptomyces conglobatus | |
| 407952 | Ionomycin, Calcium Salt, Streptomyces conglobatus |
| Accessories for Ionomycin, Free Acid, Streptomyces conglobatus |
| Product information | |||
|---|---|---|---|
| Form | Waxy solid | ||
| Molar mass | 709.0 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥90% by HPLC | ||
| Solubility | DMSO or MeOH | ||
| Chemical formula | C41H72O9 | ||
| RTECS | NO0600000 | ||
| CAS number | 56092-81-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
||
| R Phrase |
R: 22 Harmful if swallowed. |
||
