444258
MMP-14 Substrate I, Fluorogenic
MCA-PLA-C(OMeBz)-WAR(Dpa)-NH2, MT1-MMP Substrate I, Fluorogenic
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
loading
A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity. (kcat/Km = 7.3 x 105 M-1s-1 for MMP-14 (MT1-MMP) and 3.6 x 104 M-1s-1 for MMP-11 at 25°C, pH 7.5).
| Product information | |||
|---|---|---|---|
| Peptide Sequence | MCA-Pro-Leu-Ala-Cys(p-OMeBz)-Trp-Ala-Arg(Dpa)-NH2 Dpa = N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl, Bz = Benzyl | ||
| Form | Yellow lyophilized solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Molar mass | 1403.5 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥97% by HPLC | ||
| Excitation max. | ~328 nm | ||
| Emission max. | ~400 nm | ||
| Solubility | DMSO | ||
| Chemical formula | C66H82N16O17S | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
