475913
Mycophenolic Acid
6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic Acid, MPA
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
| Product information | |||
|---|---|---|---|
| Form | White to off-white solid | ||
| Molar mass | 320.4 | ||
| Purity | ≥95% by HPLC | ||
| Solubility | EtOH or 0.1 N NaOH | ||
| Chemical formula | C17H20O6 | ||
| RTECS | MP8050000 | ||
| CAS number | 24280-93-1 | ||
| Merck USA index | 14 6327 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-36 Do not breathe dust. Wear suitable protective clothing. |
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| R Phrase |
R: 20/21/22-40 Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. |
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