324813
Soluble Epoxide Hydrolase Inhibitor, NCND
CDU, N-Cyclohexyl-N′-dodecylurea, 1-Cyclohexyl-3′-dodecylurea
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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A cell-permeable 1,3-disubstituted urea compound that displays anti-hypertensive and anti-inflammatory properties. Acts as a potent, selective, competitive, and tight-binding transition-state analog inhibitor of soluble epoxide hydrolase (sEH; IC50 = 9.8 nM for mouse recombinant sEH, 85.2 nM for human recombinant sEH). Reported to decrease human VSMC (vascular smooth muscle cell) proliferation.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Molar mass | 310.5 | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by TLC | ||
| Solubility | CH2Cl2 | ||
| Chemical formula | C19H38N2O | ||
| CAS number | 402939-18-8 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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