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370695 GW1929 - CAS 196808-24-9 - Calbiochem

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).

GW1929 - CAS 196808-24-9 - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: PPAR Agonist V, PPARγ Agonist IV

Primary Target: Peroxisome proliferator-activated receptor γ (PPARγ) agonist
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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      196808-24-9C₃₀H₂₉N₃O₄
      Description
      OverviewA potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
      Catalogue Number370695
      Brand Family Calbiochem®
      SynonymsPPAR Agonist V, PPARγ Agonist IV
      References
      ReferencesHan, S., et al. 2004. Clin. Cancer Res. 10, 1911.
      Willson, T.M., et al. 2000. J. Med. Chem. 43, 527.
      Brown, K.K., et al. 1999. Diabetes 48, 1415.
      Product Information
      CAS number196808-24-9
      ATP CompetitiveN
      FormYellow crystalline solid
      Hill FormulaC₃₀H₂₉N₃O₄
      Chemical formulaC₃₀H₂₉N₃O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPeroxisome proliferator-activated receptor γ (PPARγ) agonist
      Primary Target IC<sub>50</sub>EC50 = 13 nM as peroxisome proliferator-activated receptor γ (PPARγ) agonist for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      370695 0

      Documentation

      GW1929 - CAS 196808-24-9 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      GW1929 - CAS 196808-24-9 - Calbiochem Analysenzertifikate

      TitelChargennummer
      370695

      Literatur

      Übersicht
      Han, S., et al. 2004. Clin. Cancer Res. 10, 1911.
      Willson, T.M., et al. 2000. J. Med. Chem. 43, 527.
      Brown, K.K., et al. 1999. Diabetes 48, 1415.

      Literaturstellen

      Titel
    • Iwona Bogacka, et al. (2005) Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro. Journal of Clinical Endocrinology and Metabolism in press,.
      		•
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-August-2023 JSW
      SynonymsPPAR Agonist V, PPARγ Agonist IV
      DescriptionA potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine PPARγ and 6.2 nM for human PPARγ in cell-based transactivation assays).
      FormYellow crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number196808-24-9
      Chemical formulaC₃₀H₂₉N₃O₄
      Structure formulaStructure formula
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHan, S., et al. 2004. Clin. Cancer Res. 10, 1911.
      Willson, T.M., et al. 2000. J. Med. Chem. 43, 527.
      Brown, K.K., et al. 1999. Diabetes 48, 1415.
      Citation
    • Iwona Bogacka, et al. (2005) Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro. Journal of Clinical Endocrinology and Metabolism in press,.
      		•