128635
2-Hydroxyethyl methacrylate
contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%
Synonyme(s) :
1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA
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A propos de cet article
Formule linéaire :
CH2=C(CH3)COOCH2CH2OH
Numéro CAS:
Poids moléculaire :
130.14
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
212-782-2
Beilstein/REAXYS Number:
1071583
MDL number:
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Laissez-nous vous aidervapor density
5 (vs air)
Quality Level
vapor pressure
0.01 mmHg ( 25 °C)
assay
97%
form
liquid
contains
≤250 ppm monomethyl ether hydroquinone as inhibitor
refractive index
n20/D 1.453 (lit.)
bp
67 °C/3.5 mmHg (lit.)
density
1.073 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
CC(=C)C(=O)OCCO
InChI
1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
InChI key
WOBHKFSMXKNTIM-UHFFFAOYSA-N
General description
2-Hydroxyethyl methacrylate (HEMA) was the first monomer to be used to synthesize hydrogels for biomedical applications.The water swelling properties of HEMA are enhanced by copolymerization with more hydrophilic monomers.HEMA finds wide applications for drug delivery.
Application
HEMA is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers. It is also used to prepare light responsive membranes of PHEMA, HEMA/ acrylamide based specific drug release hydrogel, and water soluble HEMA/methacrylic acid hydrogel for drug delivery. Effects of HEMA on the migration of dental pulp stem cells (in vitro) may be studied.
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Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Classe de stockage
10 - Combustible liquids
flash_point_f
222.8 °F - closed cup
flash_point_c
106 °C - closed cup
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Contenu apparenté
Influence of the ionic character of a drug on its release rate from hydrogels based on 2-hydroxyethylmethacrylate and acrylamide synthesized by photopolymerization
Gomez ML, et al.
Express Polymer Letters, 6(30, 189-197 (2012)
Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process.
Scholler K, et al.
Journal of Visualized Experiments, 85, e51680-e51680 (2014)
Drake W Williams et al.
Journal of endodontics, 39(9), 1156-1160 (2013-08-21)
Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined.