225681
4-(Diethylamino)salicylaldehyde
98%
Synonyme(s) :
4-Diethylamino-2-hydroxybenzaldehyde
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A propos de cet article
Formule linéaire :
(C2H5)2NC6H3-2-(OH)CHO
Numéro CAS:
Poids moléculaire :
193.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
241-745-3
MDL number:
Assay:
98%
Service technique
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Laissez-nous vous aiderQuality Level
assay
98%
mp
60-62 °C (lit.)
functional group
aldehyde, amine
SMILES string
CCN(CC)c1ccc(C=O)c(O)c1
InChI
1S/C11H15NO2/c1-3-12(4-2)10-6-5-9(8-13)11(14)7-10/h5-8,14H,3-4H2,1-2H3
InChI key
XFVZSRRZZNLWBW-UHFFFAOYSA-N
Application
4-(Diethylamino)salicylaldehyde was used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Classe de stockage
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Manojkumar Jadhao et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 22(1), 47-59 (2016-11-09)
Amyloid-β peptides and their metal-associated aggregated states have been implicated in the pathogenesis of Alzheimer's disease. The present paper epitomises the design and synthesis of a small, neutral, lipophilic benzothiazole Schiff base (E)-2-((6-chlorobenzo[d]thiazol-2-ylimino)methyl)-5-diethylamino)phenol (CBMDP), and explores its multifunctionalty as a
Jean Pierre Costes et al.
Inorganic chemistry, 44(6), 1973-1982 (2005-03-15)
An H2L Schiff-base ligand that was obtained from the monocondensation of diaminomaleonitrile and 4-(diethylamino)salicylaldehyde is reported together with four related nickel(II) complexes formulated as [Ni(L)(L')] (L' = MePhCHNH2, iPrNH2, Py, and PPh3). Crystal structures have been solved for H2L, [Ni(L)(MePhCHNH2)]
Takahiro Nomoto et al.
Science advances, 6(4), eaaz1722-eaaz1722 (2020-02-06)
In the current clinical boron neutron capture therapy (BNCT), p-boronophenylalanine (BPA) has been the most powerful drug owing to its ability to accumulate selectively within cancers through cancer-related amino acid transporters including LAT1. However, the therapeutic success of BPA has