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Merck

361860

Deuterium

99.8 atom % D

Synonyme(s) :

D2

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A propos de cet article

Formule linéaire :
D2
Numéro CAS:
Poids moléculaire :
4.03
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
Isotopic purity:
99.8 atom % D
Assay:
99.995% (CP)
Mass shift:
M+2
Form:
gas (compressed)
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vapor density

0.07 (vs air)

Quality Level

isotopic purity

99.8 atom % D

assay

99.995% (CP)

form

gas (compressed)

bp

-249.5 °C (lit.)

density

0.169 g/mL at -250.9 °C (liq)(lit.), 0.165 g/L at 25 °C (gas)

application(s)

electronics

mass shift

M+2

storage temp.

room temp

SMILES string

[2H][2H]

InChI

1S/H2/h1H/i1+1D

InChI key

UFHFLCQGNIYNRP-VVKOMZTBSA-N

General description

Deuterium 99.8 atom % D is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities.

Application

- Deuterium labeling for metabolic and pharmacokinetic studies
- synthesis of deuterated reference standards
- Isotope effect investigations in reaction mechanisms
- Chemical synthesis of labeled compounds

Features and Benefits

Features
- High deuterium content for effective labeling
- Versatile application in drug development
- Enhances metabolic stability of compounds
- Supports innovative pharmaceutical research

Benefits
- Accelerates drug discoverytimelines
- Improves the accuracy of pharmacokinetic studies
- Increases the robustness of formulations
- Supports the development of next-generation therapies

Packaging

All gas volumes are quoted at Normal Temperature and Pressure (NTP) and not at Standard Temperature and Pressure (STP).
Standard products are packaged in a 450 mL carbon steel lecture bottle with brass CGA 110/180 valve. Nominal gas pressures at 21ºC are 330 psig for 10 L, 850 psig for 25 L, and 1570 psig for 45 L. Care must be taken when extracting this product from the cylinder.
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Other Notes

Stainless steel control valves Z146951, Z187224 or either of stainless steel regulators Z148504 and Z148512 is recommended.
PTFE sealing washers GCA inlet size 180 Z146994
PTFE sealing washers CGA inlet size 110 Z146986


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pictograms

FlameGas cylinder

signalword

Danger

hcodes

Hazard Classifications

Flam. Gas 1A - Press. Gas Compr. Gas

Classe de stockage

2A - Gases

wgk

nwg

flash_point_f

<-238.0 °F - closed cup

flash_point_c

< -150 °C - closed cup



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Lauren E Bortolotti et al.
Ecological applications : a publication of the Ecological Society of America, 23(1), 110-121 (2013-03-19)
Hydrogen isotopes (delta2H) are often used to infer the origins of migratory animals based on the strong correlation between deuterium content of tissues and long-term patterns of precipitation. However, the extreme flood and drought dynamics of surface waters in prairie
Srinath Krishnamurthy et al.
Biochimica et biophysica acta, 1834(6), 1215-1221 (2013-03-19)
cAMP signaling is a fundamental cellular process necessary for mediating responses to hormonal stimuli. In contrast to cAMP-dependent activation of protein kinase A (PKA), an important cellular target, far less is known on termination in cAMP signaling, specifically how phosphodiesterases
Masaru Hoshino et al.
Biochimica et biophysica acta, 1768(8), 1886-1899 (2007-05-15)
A general method to analyze the structure of a supramolecular complex of amyloid fibrils at amino acid residue resolution has been developed. This method combines the NMR-detected hydrogen/deuterium (H/D) exchange technique to detect hydrogen-bonded amide groups and the ability of