440736
4-Thiouracil
97%
Synonyme(s) :
2-Hydroxy-4-mercaptopyrimidine
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A propos de cet article
Formule empirique (notation de Hill) :
C4H4N2OS
Numéro CAS:
Poids moléculaire :
128.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Form:
powder
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Laissez-nous vous aiderNom du produit
4-Thiouracil, 97%
InChI
1S/C4H4N2OS/c7-4-5-2-1-3(8)6-4/h1-2H,(H2,5,6,7,8)
SMILES string
Oc1nccc(S)n1
InChI key
OVONXEQGWXGFJD-UHFFFAOYSA-N
assay
97%
form
powder
mp
295 °C (dec.) (lit.)
solubility
1 M NaOH: soluble 50 mg/mL
Quality Level
Catégories apparentées
Application
4-Thiouracil is suitable reagent employed in Schneider′s media for the embryos during RNA extraction. It may be employed as reagent for the Northwestern blotting technique.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Qing S Wang et al.
RNA (New York, N.Y.), 11(4), 404-411 (2005-02-11)
Isolating the core functional elements of an RNA is normally performed during the characterization of a new RNA in order to simplify further biochemical analysis. The removal of extraneous sequence is challenging and can lead to biases that result from
Margaret A Nakamoto et al.
RNA (New York, N.Y.), 23(12), 1834-1849 (2017-08-31)
RNA contains over 100 modified nucleotides that are created post-transcriptionally, among which pseudouridine (Ψ) is one of the most abundant. Although it was one of the first modifications discovered, the biological role of this modification is still not fully understood.
Linda Warfield et al.
Molecular cell, 68(1), 118-129 (2017-09-19)
Previous studies suggested that expression of most yeast mRNAs is dominated by either transcription factor TFIID or SAGA. We re-examined the role of TFIID by rapid depletion of S. cerevisiae TFIID subunits and measurement of changes in nascent transcription. We find that
Jeanine S Morey et al.
PloS one, 8(6), e66347-e66347 (2013-06-19)
Dinoflagellates possess many physiological processes that appear to be under post-transcriptional control. However, the extent to which their genes are regulated post-transcriptionally remains unresolved. To gain insight into the roles of differential mRNA stability and de novo transcription in dinoflagellates
Michael R Miller et al.
Nature methods, 6(6), 439-441 (2009-05-12)
We found that the combination of spatially restricted uracil phosphoribosyltransferase (UPRT) expression with 4-thiouracil delivery can be used to label and purify cell type-specific RNA from intact complex tissues in Drosophila melanogaster. This method is useful for isolating RNA from
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