48640
Ethyl gallate
antioxidant, ≥96.0% (HPLC)
Synonyme(s) :
3,4,5-Trihydroxybenzoic acid ethyl ester, Ethyl 3,4,5-trihydroxybenzoate, Progallin A
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A propos de cet article
Formule linéaire :
3,4,5-(OH)3C6H2COOC2H5
Numéro CAS:
Poids moléculaire :
198.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-608-5
Beilstein/REAXYS Number:
2116014
MDL number:
Assay:
≥96.0% (HPLC)
Form:
solid
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Laissez-nous vous aiderQuality Level
assay
≥96.0% (HPLC)
form
solid
functional group
ester
SMILES string
CCOC(=O)c1cc(O)c(O)c(O)c1
InChI
1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3
InChI key
VFPFQHQNJCMNBZ-UHFFFAOYSA-N
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Catégories apparentées
General description
Ethyl gallate is the ethyl ester of gallic acid that belongs to a class of phenolic compound. It is an aromatic compound that is commonly used as a starting material during the synthesis of ellagic acid via transesterification reactions.
Application
Ethyl gallate is utilized as a reactant in thesynthesis of quinoxalines via sustainable green chemistry process.
- Wound healing enhancement: Ethyl gallate, isolated from Caesalpinia mimosoides, demonstrated significant effects in promoting cutaneous wound healing. This discovery supports its potential application in therapeutic treatments for skin regeneration (Bhat et al., 2023).
- Pharmacokinetics in ethanolic extracts: A study involving ethanolic extracts of Terminalia chebula, which include ethyl gallate, detailed the pharmacokinetics of these active compounds in rats, providing critical data for pharmaceutical applications and drug development processes (Yao et al., 2023).
- Ethnopharmacology research: Research on Rubus idaeus, a source of ethyl gallate, covered extensive ethnobotany, phytochemical, and pharmacological aspects, offering insights into traditional uses and modern applications, highlighting its potential in ethnopharmacology (Tao et al., 2023).
- Dermal applications: Ethyl gallate was used in a topical ointment from Caesalpinia mimosoides to attenuate dermal wounds. This application underscores its effectiveness in skin care and treatment strategies (Bhat et al., 2022).
- Neuroprotective effects: The Jingchuan tablet, which includes ethyl gallate, has been studied for its therapeutic role in treating ischaemic cerebral stroke, focusing on the HIF-1α/EPO/VEGFA signalling pathway. This research outlines its importance in neuroprotective strategies (Zhang et al., 2022).
Classe de stockage
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Anaïs Izquierdo-Llopart et al.
Foods (Basel, Switzerland), 8(1) (2019-01-13)
Cava is a sparkling wine obtained by a secondary fermentation in its own bottle. Grape skin contains several compounds, such as polyphenols, which act like natural protectors and provide flavor and color to the wines. In this paper, a previously
T Murase et al.
Arteriosclerosis, thrombosis, and vascular biology, 19(6), 1412-1420 (1999-06-11)
Gallates (gallic acid esters) belong to the class of phenolic compounds, which are abundant in red wine. In this study, we show that gallates can inhibit cytokine-induced activation of nuclear factor kappaB (NF-kappaB) and thereby reduce expression of endothelial-leukocyte adhesion
Hydroxide-Catalyzed Ellagic Acid Synthesis from Biobased Ethyl Gallate Using Deep Eutectic Solvents
Misa Mojca C, et al.
ACS sustainable chemistry & engineering, 12, 4007-4016 (2024)
Evaluation of ethyl gallate for its antioxidant and anticancer properties against chemical-induced tongue carcinogenesis in mice
Shalini M, et al.
The Biochemical Journal, 474, 3011-3025 (2017)
Steven N Mink et al.
Journal of applied physiology (Bethesda, Md. : 1985), 110(2), 359-374 (2010-11-13)
Although hydrogen peroxide (H2O2) is a well-described reactive oxygen species that is known for its cytotoxic effects and associated tissue injury, H2O2 has recently been established as an important signaling molecule. We previously demonstrated that lysozyme (Lzm-S), a mediator of
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