740292
Vitamin D3 solution
100 μg/mL in ethanol, 97% (CP)
Synonyme(s) :
Cholecalciferol solution
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A propos de cet article
Formule empirique (notation de Hill) :
C27H44O
Numéro CAS:
Poids moléculaire :
384.64
PubChem Substance ID:
eCl@ss:
34058003
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
200-578-6
MDL number:
Assay:
97% (CP)
Form:
solution
Service technique
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Laissez-nous vous aiderQuality Level
assay
97% (CP)
form
solution
concentration
100 μg/mL in ethanol
technique(s)
mass spectrometry (MS): suitable
color
colorless
mp
-144.0 °C
application(s)
detection
storage temp.
−20°C
SMILES string
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
InChI
1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key
QYSXJUFSXHHAJI-YRZJJWOYSA-N
Gene Information
human ... VDR(7421)
General description
Vitamin D3 is also known as cholecalciferol which promotes the absorption of calcium and phosphorus in the body that regulates bone growth. It is commonly found in humans and animals produced on our skin when exposed to sunlight. It facilitates bone growth and mineralization indirectly by enhancing plasma calcium and phosphorus levels. It is synthesized from 7-dehydrocholesterol, a derivative of cholesterol.
Application
Vitamin D3 is used as an internal analytical standard for the quantitation of vitamin D3 concentration in dietary supplements, fortified foods or within a complex biological matrix using a variety of testing applications.
The active metabolite of vitamin D3 is calcitriol (1,25-dihydroxyvitamin D3) encapsulated into polymeric nanoparticles, which finds the application in vitamin D3-based chemotherapy formulation study and in vitro evaluation.
The active metabolite of vitamin D3 is calcitriol (1,25-dihydroxyvitamin D3) encapsulated into polymeric nanoparticles, which finds the application in vitamin D3-based chemotherapy formulation study and in vitro evaluation.
Packaging
1 mL in ampule
hcodes
signalword
Danger
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Classe de stockage
3 - Flammable liquids
wgk
WGK 1
flash_point_f
57.2 °F - closed cup
flash_point_c
14.0 °C - closed cup
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Photometabolism of 7-dehydrocholesterol to previtamin D3 in skin
Holick, MF, et al.
Biochemical and biophysical research communications, 76(1), 107-114 (1977)
Nano-encapsulation of vitamin D 3 active metabolites for application in chemotherapy: formulation study and in vitro evaluation
Almouazen E, et al.
Pharmaceutical Research, 30(4), 1137-1146 (2013)
Yuan-Hua Chen et al.
Toxicological sciences : an official journal of the Society of Toxicology, 145(1), 90-97 (2015-02-13)
Several reports demonstrated that maternal lipopolysaccharide (LPS) exposure at middle gestational stage caused neural tube defects (NTDs). This study investigated the effects of supplementation with vitamin D3 (VitD3) during pregnancy on LPS-induced NTDs. Pregnant mice except controls were ip injected