D188700
N,N′-Dimethylthiourea
99%
Synonyme(s) :
1,3-Dimethyl-2-thiourea, 1,3-Dimethylisothiourea, Dimethylthiocarbamide
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A propos de cet article
Formule linéaire :
CH3NHCSNHCH3
Numéro CAS:
Poids moléculaire :
104.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-588-2
Beilstein/REAXYS Number:
605454
MDL number:
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N,N′-Dimethylthiourea, 99%
InChI
1S/C3H8N2S/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)
InChI key
VLCDUOXHFNUCKK-UHFFFAOYSA-N
SMILES string
CNC(=S)NC
assay
99%
form
crystals
Quality Level
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Catégories apparentées
Application
- Pharmaceutical Analysis: Mao et al. developed an itaconic acid-based organic-polymer monolithic column for hydrophilic capillary electrochromatography, which was used in pharmaceutical analysis. N,N′-Dimethylthiourea could be utilized to improve the column′s performance by acting as a potential organic modifier to enhance the separation processes (Mao et al., 2024).
- Agricultural Research: Li et al. examined the effect of the reactive oxygen scavenger N,N′-Dimethylthiourea on seed germination and radicle elongation of maize. This research could help in understanding how this chemical can be used to influence plant growth under stress conditions, potentially improving agricultural productivity (Li et al., 2023).
General description
N,N′-Dimethylthiourea, also known as 1,3-Dimethylisothiourea, is commonly used in organic reactions to synthesize N-containing compounds such as N-acyl-substituted 1,1-diaminoethylenes, amidines, ureas, and thioureas. It also acts as a nucleophilic catalyst in the bromination of alcohols using N-bromosuccinimide (NBS), during the conversion to the corresponding bromides.
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Synthesis, Characterization, and Reactivity of N-Acyl Chloroformamidines: Useful Building Blocks for the Construction of N-Acyl-Substituted 1, 1-Diaminoethylenes, Amidines, Ureas, and Thioureas
Yang W, et al.
Synthesis, 45, 347-354 (2013)
Crystal structure of the 1: 2 adduct of bis (piperidinium) sulfate and 1, 3-dimethylthiourea
Cindy D, et al.
Acta Crystallographica Section E: Crystallographic Communications, 73, 651-653 (2017)
Thiourea-mediated halogenation of alcohols
Amar M R, et al.
The Journal of Organic Chemistry, 85, 12901-12911 (2020)
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Nanomaterials (Basel, Switzerland), 9(12) (2019-12-15)
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Cytochrome c (cyt c) is known for its role in the electron transport chain but transitions to a peroxidase-active state upon exposure to oxidative species. The peroxidase activity ultimately results in the release of cyt c into the cytosol for
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