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Merck

850345C

Avanti

14:0 PC (DMPC)

Avanti Research - A Croda Brand

Synonyme(s) :

1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)

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A propos de cet article

Formule empirique (notation de Hill) :
C36H72NO8P
Numéro CAS:
Poids moléculaire :
677.93
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Nom du produit

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850345C-25mg), pkg of 1 × 20 mL (850345C-500mg), pkg of 2 × 20 mL (850345C-1g), pkg of 2 × 4 mL (850345C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850345C

concentration

10 mg/mL (850345C-25mg), 25 mg/mL (850345C-1g), 25 mg/mL (850345C-200mg), 25 mg/mL (850345C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@@H](OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1

InChI key

CITHEXJVPOWHKC-UMSFTDKQSA-N

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

14:0 PC (DMPC) has been used in liposome preparation. It is also suitable for use:
  • in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
  • in labeled vesicle preparation for fluorescence polarization measurements
  • as internal standard (IS) for the quantitation of phosphatidylcholine (PC) by liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-1g)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-500mg)
5 mL Clear Glass Sealed Ampule (850345C-200mg)
5 mL Clear Glass Sealed Ampule (850345C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash



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